BDBM235027 5-fluoro-4-(4-fluoro-1-(2-methyl-6-(trifluoromethyl)benzyl)-1H-indazol-3-yl)-2-hydroxybenzoic acid (8A) and 5-fluoro-4-(4-fluoro-1-(2-(trifluoromethyl)benzyl)-1H-indazol-3-yl)-2-hydroxybenzoic acid (8B)::US9556168, 8A
SMILES COC(=O)c1cc(F)c(cc1O)-c1nn(Cc2c(C)cccc2C(F)(F)F)c2cccc(F)c12
InChI Key InChIKey=LZOKQMKUURPOHI-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 235027
Affinity DataIC50: 15nMpH: 7.0Assay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair