BDBM235031 US9556168, 10A::sodium 4-(1-(2-chloro-6-(trifluoromethyl)benzyl)-4-fluoro-6-(3-methoxyazetidine-1-carbonyl)-1H-indazol-3-yl)-5-fluoro-2-hydroxybenzoate (10A)

SMILES COC1CN(C1)C(=O)c1cc(F)c2c(nn(Cc3c(Cl)cccc3C(F)(F)F)c2c1)-c1cc(O)c(cc1F)C([O-])=O

InChI Key InChIKey=AYOPYSVFEDRFSQ-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235031   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235031(US9556168, 10A | sodium 4-(1-(2-chloro-6-(trifluor...)
Affinity DataIC50:  4nMpH: 7.0Assay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent