BDBM236201 US9365563, U5::US9878991, Compound U5

SMILES OC[C@H](O)c1cnc(c(Cl)c1)C1(F)CCN(CC1)C(=O)Nc1ccc(c(F)c1)C(F)(F)F

InChI Key InChIKey=LGBXVEHTLHONOH-INIZCTEOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 236201   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM236201(US9365563, U5 | US9878991, Compound U5)
Affinity DataIC50:  19.9nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM236201(US9365563, U5 | US9878991, Compound U5)
Affinity DataIC50:  19.9nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent