BDBM236464 US9365576, 220
SMILES CCOC(=O)c1c2C(=O)N(C(c2n(C(C)C)c1-c1cnc(OC)nc1OC)c1ccc(Cl)cc1)c1cc(Cl)c(=O)n(C)c1
InChI Key InChIKey=NOEHJSJYFPPOPM-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 236464
TargetCellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 0.134nMT: 2°CAssay Description:Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...More data for this Ligand-Target Pair