BDBM236564 US9365582, 4
SMILES CCOc1cc(O[C@@H]2C[C@@H]3[C@@H](C2)C(=O)N(C)CCCC\C=C/[C@@H]2C[C@]2(NC3=O)C(O)=O)c2ccc(OC)cc2n1
InChI Key InChIKey=QNVCYCOYQOYHKP-CKHWJCSMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 236564
TargetGenome polyprotein [1027-1711](Hepatitis C virus genotype 1a (strain H77) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataKi: 46nMpH: 7.5Assay Description:The inhibition of full-length hepatitis C NS3 protease enzyme was measured essentially as described in Poliakov, 2002 Prot Expression & Purification ...More data for this Ligand-Target Pair
TargetGenome polyprotein [1027-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataEC50: 4.26E+3nMAssay Description:The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...More data for this Ligand-Target Pair