BDBM236792 US9388149, 1 (Diastereoisomer 1)::US9388149, 1 (Diastereoisomer 2)::US9388149, 1 (Enantiomer 2 of diastereoisomer 2)

SMILES CN(C)C(=O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3(C)CCCO3)c(=O)c2=O)c1O

InChI Key InChIKey=VWSXKWXISJLOQM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 236792   

TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM236792(US9388149, 1 (Diastereoisomer 1) | US9388149, 1 (D...)
Affinity DataIC50:  244nMT: 2°CAssay Description:⿿PathHunter HEK293-CXCR2⿝ or ⿿U2OS hCXCR1 β-arrestin⿝ cells (DiscoveRx Corporation) were seeded overnight at 10 000 cells/well (384-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM236792(US9388149, 1 (Diastereoisomer 1) | US9388149, 1 (D...)
Affinity DataIC50:  2.08E+3nMT: 2°CAssay Description:⿿PathHunter HEK293-CXCR2⿝ or ⿿U2OS hCXCR1 β-arrestin⿝ cells (DiscoveRx Corporation) were seeded overnight at 10 000 cells/well (384-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM236792(US9388149, 1 (Diastereoisomer 1) | US9388149, 1 (D...)
Affinity DataIC50:  94nMT: 2°CAssay Description:⿿PathHunter HEK293-CXCR2⿝ or ⿿U2OS hCXCR1 β-arrestin⿝ cells (DiscoveRx Corporation) were seeded overnight at 10 000 cells/well (384-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM236792(US9388149, 1 (Diastereoisomer 1) | US9388149, 1 (D...)
Affinity DataIC50:  53nMT: 2°CAssay Description:⿿PathHunter HEK293-CXCR2⿝ or ⿿U2OS hCXCR1 β-arrestin⿝ cells (DiscoveRx Corporation) were seeded overnight at 10 000 cells/well (384-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM236792(US9388149, 1 (Diastereoisomer 1) | US9388149, 1 (D...)
Affinity DataIC50:  89nMT: 2°CAssay Description:⿿PathHunter HEK293-CXCR2⿝ or ⿿U2OS hCXCR1 β-arrestin⿝ cells (DiscoveRx Corporation) were seeded overnight at 10 000 cells/well (384-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM236792(US9388149, 1 (Diastereoisomer 1) | US9388149, 1 (D...)
Affinity DataIC50:  819nMT: 2°CAssay Description:⿿PathHunter HEK293-CXCR2⿝ or ⿿U2OS hCXCR1 β-arrestin⿝ cells (DiscoveRx Corporation) were seeded overnight at 10 000 cells/well (384-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent