BDBM236810 US9388149, 8 (Diastereoisomer 1)

SMILES CN(CC(F)(F)F)C(=O)c1cccc(Nc2c(N[C@@H](C3CCCS3)c3ccc(C)o3)c(=O)c2=O)c1O

InChI Key InChIKey=KBLOFZHBIDLNIS-ZYMOGRSISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 236810   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM236810(US9388149, 8 (Diastereoisomer 1))
Affinity DataIC50:  115nMT: 2°CAssay Description:⿿PathHunter HEK293-CXCR2⿝ or ⿿U2OS hCXCR1 β-arrestin⿝ cells (DiscoveRx Corporation) were seeded overnight at 10 000 cells/well (384-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM236810(US9388149, 8 (Diastereoisomer 1))
Affinity DataIC50:  508nMT: 2°CAssay Description:⿿PathHunter HEK293-CXCR2⿝ or ⿿U2OS hCXCR1 β-arrestin⿝ cells (DiscoveRx Corporation) were seeded overnight at 10 000 cells/well (384-well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent