BDBM237369 US10052306, 185::rac-(3aR,5r,6aS)-2-(2- hydroxy-2-(4- hydroxyphenyl)ethyl)-5- (2- methylbenzyl)octahydro- cyclopenta[c]pyrrol-5-ol

SMILES Cc1ccccc1C[C@@]1(O)C[C@@H]2CN(CC(O)c3ccc(O)cc3)C[C@@H]2C1

InChI Key InChIKey=GEHSEHIQQRCQDG-WVTBVLOCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237369   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Cadent Therapeutics

US Patent
LigandPNGBDBM237369(US10052306, 185 | rac-(3aR,5r,6aS)-2-(2- hydroxy-2...)
Affinity DataIC50:  34.9nMAssay Description:To each well of the plate, 10 μL test compound, control (MK801) or HHnoCa buffer was added to a final concentration of 10 μM with a final c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent