BDBM237408 US9393232, 1.16

SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(O)(C3CCOCC3)c2c1

InChI Key InChIKey=GHYCWVRIEDGGFQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 237408   

TargetBromodomain-containing protein 2 [1-473](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM237408(US9393232, 1.16)
Affinity DataIC50:  380nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [1-397](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM237408(US9393232, 1.16)
Affinity DataIC50:  510nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM237408(US9393232, 1.16)
Affinity DataIC50:  630nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 3 [1-435](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM237408(US9393232, 1.16)
Affinity DataIC50:  140nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent