BDBM237461 US9393232, 2.37::US9393232, 2.37a::US9393232, 2.37b

SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(N)(C3CCCCC3)c2c1

InChI Key InChIKey=TYYNTGOPTCKZTN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 237461   

TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM237461(US9393232, 2.37 | US9393232, 2.37a | US9393232, 2....)
Affinity DataIC50:  93nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM237461(US9393232, 2.37 | US9393232, 2.37a | US9393232, 2....)
Affinity DataIC50:  1.10E+3nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM237461(US9393232, 2.37 | US9393232, 2.37a | US9393232, 2....)
Affinity DataIC50:  54nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent