BDBM237516 US9393232, 2.17::US9393232, 2.17a::US9393232, 2.17b

SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(N3CCC[C@@H](O)C3)(c2c1)c1ccccc1

InChI Key InChIKey=UXFXOEGGFKVCDW-PHSANKKPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 237516   

TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM237516(US9393232, 2.17 | US9393232, 2.17a | US9393232, 2....)
Affinity DataIC50:  40nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM237516(US9393232, 2.17 | US9393232, 2.17a | US9393232, 2....)
Affinity DataIC50:  26nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM237516(US9393232, 2.17 | US9393232, 2.17a | US9393232, 2....)
Affinity DataIC50:  27nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent