BDBM238826 US9394297, 513

SMILES CCn1c(NC2(C)CC2)nc2c(-c3cc4C(=O)N[C@H](C)c4[nH]3)c(F)ccc2c1=O

InChI Key InChIKey=DVKOJQHRIKGCMQ-SNVBAGLBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238826   

TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM238826(US9394297, 513)
Affinity DataIC50:  0.0378nMpH: 7.0 T: 2°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM238826(US9394297, 513)
Affinity DataIC50:  0.0130nMpH: 7.0 T: 2°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent