BDBM238901 US9403827, 3

SMILES COc1ccccc1-c1nc2NC(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)ccc1C

InChI Key InChIKey=PHETUTHFDPFIRQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238901   

TargetE3 ubiquitin-protein ligase Mdm2 [2-188]/Protein Mdm4 [2-185](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM238901(US9403827, 3)
Affinity DataIC50:  1.45E+3nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM238901(US9403827, 3)
Affinity DataIC50:  1.80nMT: 2°CAssay Description:Assay 1: This assay was used to evaluate compounds displaying inhibition of p53-MDM2 interaction and p53-MDM4 interaction at IC50s of 0.005 to 50 &mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent