BDBM239039 US10028934, Compound 28::US10478423, Cpd. 28::US9408850, 28::US9597317, 28

SMILES O=C(Nc1n[nH]c2cc(OCCOCc3ccccc3)ccc12)c1ccc(cc1)N1CC(C1)N1CCCC1

InChI Key InChIKey=SWXOORVKAHJWLM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 239039   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239039(US10028934, Compound 28 | US10478423, Cpd. 28 | US...)
Affinity DataIC50:  136nMpH: 7.9Assay Description:i. Enzyme The assay was performed using FLT3 cytoplasmic domain product and purified in house as GST fused protein. The FLT3 protein (1 microM) was p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM239039(US10028934, Compound 28 | US10478423, Cpd. 28 | US...)
Affinity DataIC50:  306nMpH: 7.9Assay Description:i. Enzyme The assay has been performed using KIT cytoplasmic domain product and purified in house as GST fused protein. The KIT protein (4.5 microM) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent