BDBM239595 US9394309, 48
SMILES CN1CCN(CC1)c1cc(cc(c1)C(C)(C)C)C(=O)Nc1ccc(C)c(c1)-n1ccn2nc(cc12)-c1cccnc1
InChI Key InChIKey=JDAGUKZTZYWGAN-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 239595
TargetAngiopoietin-1 receptor [776-1124](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft
US Patent
Bayer Pharma Aktiengesellschaft
US Patent
Affinity DataIC50: 6.40nMpH: 9.6 T: 2°CAssay Description:For measuring the autophosphorylation of the endogenous Tie2 receptor in the cell lysates prepared, a self-prepared anti-Tie2 antibody directed again...More data for this Ligand-Target Pair
TargetAngiopoietin-1 receptor [776-1124](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft
US Patent
Bayer Pharma Aktiengesellschaft
US Patent
Affinity DataIC50: 0.300nMpH: 7.0 T: 2°CAssay Description:For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...More data for this Ligand-Target Pair