BDBM239815 Roche-Dataset for PDE10A, Compound 119::US9394311, 98
SMILES Cc1c(Cl)cc(OCC(F)(F)F)c2nc(CCc3nc(nn3C)N3CCCC3)nn12
InChI Key InChIKey=NTIUYJNMDUZGAG-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 239815
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche
F. Hoffmann-La Roche
Affinity DataIC50: 0.5nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair