BDBM240262 US9403843, 33

SMILES OC(=O)[C@@H]1O[C@H]1C(=O)N[C@@H](Cc1cscn1)C(=O)Nc1nc(cs1)-c1ccc(F)cc1

InChI Key InChIKey=WRGOUJJZKXTKBL-NWANDNLSSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240262   

TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM240262(US9403843, 33)
Affinity DataKi:  2.60E+3nM ΔG°:  -7.74kcal/molepH: 7.6 T: 2°CAssay Description:Full length porcine calpain (156 nM), or papain (236 pM) was added to a solution of 100 mM NaCl, 50 mM HEPES, pH 7.6, 1 mM TCEP, 30 μM Suc-LLVY-AM...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM240262(US9403843, 33)
Affinity DataIC50:  100nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent