BDBM241941 US9422333, I-6

SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#8]C([#6])([#6])[#6])-[#6](=O)-[#7]-1-[#6]-[#6]2-[#6@@H](-[#6@H]-1-[#6](=O)-[#7]-[#6](-[#6]-[#6]-1-[#6]-[#6]-[#6]-1)-[#6](=O)-[#6](-[#7])=O)C2([#6])[#6]

InChI Key InChIKey=YHPGGDKFNAIFIV-AGYXVXSJSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 241941   

TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50:  53nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,D168A](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50:  25nMpH: 7.8 T: 2°CAssay Description:The protocol is a modified FRET-based assay (v_02) from In Vitro Resistance Studies of HCV Serine Protease Inhibitors, 2004, JBC, vol. 279, No. 17, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50:  456nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,C159S](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50:  2.07E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,D168A](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50:  321nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,R155K](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50:  1.05E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-1207,A156S](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Celgene Avilomics Research

US Patent
LigandPNGBDBM241941(US9422333, I-6)
Affinity DataIC50: >3.00E+3nMpH: 7.5Assay Description:The protocol is a modified FRET-based assay (v_03) developed to evaluate compound potency, rank-order and resistance profiles against wild type and C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent