BDBM242353 US10047093, 8-9::US10392392, Example 8-9::US10875864, EX. 8-9::US9416132, 8-9
SMILES C[C@]1(O)CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(OC(F)(F)F)c3)n2n1
InChI Key InChIKey=YVGAENJCKBRBJB-QUWSVYMGSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 242353
Affinity DataIC50: 13nMT: 2°CAssay Description:These assays are set up in duplicate 50 ul volumes in white, flat bottom 96 well plates. Inhibitors are added to the solution of 1× kinase buff...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tolero Pharmaceuticals
US Patent
Tolero Pharmaceuticals
US Patent
Affinity DataIC50: 2.60E+4nMAssay Description:Representative compounds were tested for hERG activity using the Fast Patch assay available from WuXiApptec (Shanghai China).More data for this Ligand-Target Pair
Affinity DataIC50: 13nMT: 2°CAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tolero Pharmaceuticals
US Patent
Tolero Pharmaceuticals
US Patent
Affinity DataIC50: 2.60E+4nMAssay Description:Representative compounds were tested for hERG activity using the Fast Patch assay available from WuXiApptec (Shanghai China). More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tolero Pharmaceuticals
US Patent
Tolero Pharmaceuticals
US Patent
Affinity DataIC50: 2.60E+4nMAssay Description:hERG activity assays representative compounds were tested for hERG activity using the Fast Patch assay available from WuXiApptec (Shanghai China). More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tolero Pharmaceuticals
US Patent
Tolero Pharmaceuticals
US Patent
Affinity DataIC50: 2.60E+4nMAssay Description:Representative compounds were tested for hERG activity using the Fast Patch assay available from WuXiApptec (Shanghai China).More data for this Ligand-Target Pair