BDBM242374 US10047093, 8-31::US10392392, Example 8-31::US10875864, EX. 8-31::US9416132, 8-31
SMILES CC(C)(O)[C@H]1CC[C@@H](CC1)Nc1ccc2ncc(-c3cccc(c3)C(F)(F)F)n2n1
InChI Key InChIKey=XRNVABDYQLHODA-JCNLHEQBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 242374
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Inhibition of PIM1 (unknown origin) up to 120 mins by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tolero Pharmaceuticals
US Patent
Tolero Pharmaceuticals
US Patent
Affinity DataIC50: >3.00E+4nMAssay Description:Representative compounds were tested for hERG activity using the Fast Patch assay available from WuXiApptec (Shanghai China).More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1nMT: 2°CAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tolero Pharmaceuticals
US Patent
Tolero Pharmaceuticals
US Patent
Affinity DataIC50: >3.00E+4nMAssay Description:Representative compounds were tested for hERG activity using the Fast Patch assay available from WuXiApptec (Shanghai China).More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tolero Pharmaceuticals
US Patent
Tolero Pharmaceuticals
US Patent
Affinity DataIC50: >3.00E+4nMAssay Description:Representative compounds were tested for hERG activity using the Fast Patch assay available from WuXiApptec (Shanghai China). More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tolero Pharmaceuticals
US Patent
Tolero Pharmaceuticals
US Patent
Affinity DataIC50: >3.00E+4nMAssay Description:hERG activity assays representative compounds were tested for hERG activity using the Fast Patch assay available from WuXiApptec (Shanghai China). More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1nMT: 2°CAssay Description:These assays are set up in duplicate 50 ul volumes in white, flat bottom 96 well plates. Inhibitors are added to the solution of 1× kinase buff...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nri Institute Of Pharmacy
Curated by ChEMBL
Nri Institute Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:One illustrative manner in which Pim-1 kinase activity can be determined is by quantifying the amount of ATP remaining in solution after an in vitro ...More data for this Ligand-Target Pair