BDBM242558 US9422240, 1-353

SMILES OC(=O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3ccc(Cl)cc3)nc2)C1=O

InChI Key InChIKey=HMMHKGLPKAQOOH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 242558   

TargetEgl nine homolog 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM242558(US9422240, 1-353)
Affinity DataIC50:  43nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEgl nine homolog 1(Rattus norvegicus (Rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM242558(US9422240, 1-353)
Affinity DataIC50:  18nMAssay Description:Inhibition of rat PHD2 using FITC-HIF1-alpha as substrate after 10 mins in presence of 2-oxoglutarate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM242558(US9422240, 1-353)
Affinity DataIC50:  13nMAssay Description:Inhibition of human PHD2 using FITC-HIF1-alpha as substrate after 10 mins in presence of 2-oxoglutarate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed