BDBM242568 US9422240, 1-378

SMILES CC(C)c1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cn2)cc1

InChI Key InChIKey=KKYALXLCAJCKGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 242568   

TargetEgl nine homolog 1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM242568(US9422240, 1-378)
Affinity DataIC50:  14nMAssay Description:Inhibition of human PHD2 expressed in 293FT cells using HIF-1 [alpha] as substrate after 20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM242568(US9422240, 1-378)
Affinity DataIC50:  14nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent