BDBM242568 US9422240, 1-378
SMILES CC(C)c1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cn2)cc1
InChI Key InChIKey=KKYALXLCAJCKGY-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 242568
Affinity DataIC50: 14nMAssay Description:Inhibition of human PHD2 expressed in 293FT cells using HIF-1 [alpha] as substrate after 20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 7.5Assay Description:The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...More data for this Ligand-Target Pair