BDBM243451 US9427428, 15::US9433609, 15

SMILES COC(=O)N[C@@H](C1CCCC1)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C1CCCC1

InChI Key InChIKey=DSANXDOJTRZSQT-GEOLJVLKSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 243451   

TargetGenome polyprotein [810-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243451(US9427428, 15 | US9433609, 15)
Affinity DataEC50:  0.00300nMAssay Description:The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-3011](Hepatitis C virus genotype 1a (isolate H) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243451(US9427428, 15 | US9433609, 15)
Affinity DataEC50:  0.277nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1973-2419,Y2165H](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243451(US9427428, 15 | US9433609, 15)
Affinity DataEC50:  1.19nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1973-2419,Y2165H](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243451(US9427428, 15 | US9433609, 15)
Affinity DataEC50:  1.19nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1657-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243451(US9427428, 15 | US9433609, 15)
Affinity DataEC50:  0.00300nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1657-3011](Hepatitis C virus genotype 1a (isolate H77) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243451(US9427428, 15 | US9433609, 15)
Affinity DataEC50:  0.277nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1657-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243451(US9427428, 15 | US9433609, 15)
Affinity DataEC50:  0.00300nMAssay Description:The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent