BDBM243462 US9427440, 3
SMILES COc1ccc2-c3c(C4CCCCC4)c4ccc5cc4n3C[C@@H](Cc2c1)C(=O)N(C)CCOCCN(C)S(=O)(=O)NC5=O
InChI Key InChIKey=JYIVMQPLCGSFGI-XMMPIXPASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 243462
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataIC50: 530nMT: 2°CAssay Description:IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr...More data for this Ligand-Target Pair
TargetGenome polyprotein [1027-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataEC50: 79nMAssay Description:The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...More data for this Ligand-Target Pair