BDBM24361 2,3-dichloro-N-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)-4H-thieno[3,2-b]pyrrole-5-carboxamide::3,4-dihydro-2-quinolone (DHQ) derivative, 1::CHEMBL373749

SMILES Clc1sc2cc([nH]c2c1Cl)C(=O)NC1Cc2ccccc2NC1=O

InChI Key InChIKey=VIXSCUOQQOJRRG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24361   

TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM24361(2,3-dichloro-N-(2-oxo-1,2,3,4-tetrahydroquinolin-3...)
Affinity DataIC50:  132nMAssay Description:Inhibition of recombinant human liver GPa by multienzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM24361(2,3-dichloro-N-(2-oxo-1,2,3,4-tetrahydroquinolin-3...)
Affinity DataIC50:  132nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the test compounds against human recombinant glycogen phosphorylase a (GPa) was monitored using 96-well microplate format....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed