BDBM24387 3,4-dihydro-2-quinolone (DHQ) derivative, 26::5-chloro-N-[1-(2-hydroxyethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl]-1H-indole-2-carboxamide

SMILES OCCN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key InChIKey=KCMCGGMTGBVPCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24387   

TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM24387(3,4-dihydro-2-quinolone (DHQ) derivative, 26 | 5-c...)
Affinity DataIC50:  17nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the test compounds against human recombinant glycogen phosphorylase a (GPa) was monitored using 96-well microplate format....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed