BDBM244117 US9428492, 1::US9428492, 2

SMILES C[C@@H](O)c1nc(C)nn1-c1cc(nc(C)n1)N1CC(C1)c1nc2ccccc2n1C

InChI Key InChIKey=MGSBZMYABLCAOB-GFCCVEGCSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 244117   

LigandPNGBDBM244117(US9428492, 1 | US9428492, 2)
Affinity DataKi:  0.230nM ΔG°:  -13.1kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM244117(US9428492, 1 | US9428492, 2)
Affinity DataKi:  1.20nM ΔG°:  -12.2kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244117(US9428492, 1 | US9428492, 2)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition assay using CYP2C9More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244117(US9428492, 1 | US9428492, 2)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition assay using CYP2C9More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent