BDBM244121 US9428492, 4::US9428492, 4a::US9428492, 4b

SMILES CCC(O)c1nc(C)nn1-c1cc(nc(C)n1)N1CC(C1)c1nc2ccccc2n1C

InChI Key InChIKey=WSLFTXBMJFPNHV-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 244121   

LigandPNGBDBM244121(US9428492, 4 | US9428492, 4a | US9428492, 4b)
Affinity DataKi:  0.410nM ΔG°:  -12.8kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM244121(US9428492, 4 | US9428492, 4a | US9428492, 4b)
Affinity DataKi:  0.510nM ΔG°:  -12.7kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM244121(US9428492, 4 | US9428492, 4a | US9428492, 4b)
Affinity DataKi:  1.80nM ΔG°:  -11.9kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244121(US9428492, 4 | US9428492, 4a | US9428492, 4b)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition assay using CYP2C9More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent