BDBM244147 US9428492, 17
SMILES C[C@H](O)c1nc(C)nn1-c1cc(nc(n1)C(F)(F)F)C1C[C@H]1c1nc2ccccc2n1C
InChI Key InChIKey=PIPXXCIAJLPPBJ-RDWQBYKPSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 244147
TargetIsoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 2.80nM ΔG°: -11.7kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair