BDBM244155 US9428492, A
SMILES Cc1nc(n(n1)-c1cc(nc(C)n1)C1C[C@H]1c1nc2ccccc2n1C)C(C)(C)O
InChI Key InChIKey=HMJGDWOLEDIDLX-YSSOQSIOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 244155
TargetIsoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 4.20nM ΔG°: -11.4kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition assay using CYP2C9More data for this Ligand-Target Pair