BDBM244157 US9428492, C

SMILES COCc1nc(C)nn1-c1cc(nc(C)n1)C1C[C@H]1c1nc2ccccc2n1C

InChI Key InChIKey=BCXVMJGBVMARTJ-YSSOQSIOSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244157   

LigandPNGBDBM244157(US9428492, C)
Affinity DataKi:  0.490nM ΔG°:  -12.7kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244157(US9428492, C)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition assay using CYP2C9More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent