BDBM244218 US9546173, cmpd 157::n-(2-(dimethylamino)ethyl)-5,5-dimethyl-2-(phenylamino)-5h-pyrrolo[3,4-d]pyrimidine-6(7h)-carboxamide

SMILES CN(C)CCNC(=O)N1Cc2nc(Nc3ccccc3)ncc2C1(C)C

InChI Key InChIKey=LUDKWAUIQZCITP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244218   

TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM244218(US9546173, cmpd 157 | n-(2-(dimethylamino)ethyl)-5...)
Affinity DataIC50:  3.85E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM244218(US9546173, cmpd 157 | n-(2-(dimethylamino)ethyl)-5...)
Affinity DataIC50:  2.50E+4nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent