BDBM24454 1-(3-fluoro-4-methoxyphenyl)-N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}phenyl)-5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxamide::4-pyridone analogue, 43
SMILES COc1ccc(cc1F)-n1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c(=O)c(c1)-c1ccc(F)cc1
InChI Key InChIKey=RWIBXRLRFKBBLR-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 24454
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...More data for this Ligand-Target Pair