BDBM245534 US9428503, 62

SMILES CO[C@@H]1CC[C@H](C1)n1c2c(cnc3cc(F)c(cc23)-c2ccc(OCCCN(C)C)nc2)n(C)c1=O

InChI Key InChIKey=UAWYNAAMALKRLO-RTBURBONSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245534   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM245534(US9428503, 62)
Affinity DataIC50: >3.00E+4nMT: 2°CAssay Description:Assay d) MDA-MB-468 cells (human breast adenocarcinoma ##ATCC HTB 132) were seeded at 1500 cells/well in 40 μl of DMEM containing 10% FBS and 1% g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM245534(US9428503, 62)
Affinity DataIC50:  0.507nMT: 2°CAssay Description:Assay a) HT29 cells (ECACC #85061109) were seeded into 384 well assay plates (Costar #3712) at a density of 3500 cells/well in 40 μl EMEM medium c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent