BDBM245545 US9428503, 69

SMILES CO[C@H]1CC[C@@H](C1)n1c2c(cnc3ccc(cc23)-c2ccc(OCCCN(C)C)nc2F)n(C)c1=O

InChI Key InChIKey=QNJITDREARMZMY-OALUTQOASA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 245545   

TargetSerine-protein kinase ATM(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM245545(US9428503, 69)
Affinity DataIC50:  0.324nMT: 2°CAssay Description:Assay a) HT29 cells (ECACC #85061109) were seeded into 384 well assay plates (Costar #3712) at a density of 3500 cells/well in 40 μl EMEM medium c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM245545(US9428503, 69)
Affinity DataIC50: >2.77E+3nMT: 2°CAssay Description:Assay c) BT474 cells (human breast ductal carcinoma, ATCC HTB-20) were seeded into black 384 well plates (Costar, #3712) at a density of 5600 cells/w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM245545(US9428503, 69)
Affinity DataIC50: >3.00E+4nMT: 2°CAssay Description:Assay b) HT29 cells (ECACC #85061109) were seeded into 384 well assay plates (Costar #3712) at a density of 6000 cells/well in 40 μl EMEM medium c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent