BDBM245585 US9428508, 40::US9428508, 46

SMILES COc1cc(ccc1Nc1nc2NCCc2c(Nc2ccccc2S(=O)(=O)NC(C)C)n1)N1CCOCC1

InChI Key InChIKey=KHFFMLFDJBHXPO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 245585   

TargetFocal adhesion kinase 1(Homo sapiens (Human))
Centaurus Biopharma

US Patent
LigandPNGBDBM245585(US9428508, 40 | US9428508, 46)
Affinity DataIC50: <20nMAssay Description:To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Centaurus Biopharma

US Patent
LigandPNGBDBM245585(US9428508, 40 | US9428508, 46)
Affinity DataIC50: <20nMAssay Description:To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Centaurus Biopharma

US Patent
LigandPNGBDBM245585(US9428508, 40 | US9428508, 46)
Affinity DataIC50: <20nMAssay Description:To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Centaurus Biopharma

US Patent
LigandPNGBDBM245585(US9428508, 40 | US9428508, 46)
Affinity DataIC50: <20nMAssay Description:To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent