BDBM245763 US9428511, 55

SMILES CC[C@@H]1CN(CC[C@H]1Nc1c(cnn2cc(nc12)-c1cnn(CC)c1)C(N)=O)c1ccc(nn1)C#N

InChI Key InChIKey=FSGDGKSWPWYXJK-DNVCBOLYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245763   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM245763(US9428511, 55)
Affinity DataIC50:  0.200nMpH: 7.4 T: 2°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM245763(US9428511, 55)
Affinity DataIC50:  0.5nMpH: 7.4 T: 2°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent