BDBM24586 (1R)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}dodecyl N-formylglycinate::(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl 2-formamidoacetate::CHEMBL458827::Orlistat derivative, 15g::Orlistat derivative, 17c
SMILES CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)CNC=O
InChI Key InChIKey=ANPULBVRORHAGO-VABKMULXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 24586
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB2 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant DAGLalpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey ...More data for this Ligand-Target Pair
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant human MAGL expressed in African green monkey COS7 cells using 2-arachidonoyl-[3H]-glycerol as substrate after 20 mins by sc...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of FAAH-mediated [14C]anadamide hydrolysis in rat brain membraneMore data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 1.72E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research
The Burnham Institute For Medical Research
Affinity DataIC50: 1.02E+3nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair