BDBM245975 US9433622, DMX- 72
SMILES COCCNc1cc(Nc2nccc(n2)-c2cnc(N3CC[C@H](F)C3)c(c2)C#N)ccn1
InChI Key InChIKey=CVAKBVASVPZLKY-KRWDZBQOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 245975
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <15nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: <30nMpH: 7.5Assay Description:Kinase inhibition assays (10 μL) were performed at 20° C. in 384-well plate format. Compound IC50 values were determined at the apparent Km for ...More data for this Ligand-Target Pair