BDBM246464 US9447114, 25

SMILES Cc1c(sc2n(C)c(=O)n(CCCO)c(=O)c12)-c1ccc(Cl)cc1

InChI Key InChIKey=WQRGHSSPNYUZEW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 246464   

TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Hydra Biosciences

US Patent
LigandPNGBDBM246464(US9447114, 25)
Affinity DataIC50:  15.7nMpH: 7.2Assay Description:TRPC5 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Hydra Biosciences

US Patent
LigandPNGBDBM246464(US9447114, 25)
Affinity DataIC50:  168nMpH: 7.4 T: 2°CAssay Description:The commercially available HEK293/TREx line (Invitrogen) was stably transfected with a TRPC5 construct and screened by conventional calcium imaging t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent