BDBM246485 Tristin (1)

SMILES COc1cc(CCc2cc(O)cc(O)c2)ccc1O

InChI Key InChIKey=KPFFMALTIRFAHW-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 246485   

TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Seoul National University

LigandPNGBDBM246485(Tristin (1))
Affinity DataKi:  2.75E+3nM ΔG°:  -7.89kcal/mole IC50:  1.35E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246485(Tristin (1))
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of ovine COX1 by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM246485(Tristin (1))
Affinity DataIC50:  2.12E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246485(Tristin (1))
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed