BDBM246486 3,3',5-Trihydroxy-2'-methoxybibenzyl (3)

SMILES COc1c(O)cccc1CCc1cc(O)cc(O)c1

InChI Key InChIKey=FNNQAZPVTHKZOI-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 246486   

TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Seoul National University

LigandPNGBDBM246486(3,3',5-Trihydroxy-2'-methoxybibenzyl (3))
Affinity DataKi:  1.82E+3nM ΔG°:  -8.14kcal/mole IC50:  8.77E+3nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246486(3,3',5-Trihydroxy-2'-methoxybibenzyl (3))
Affinity DataIC50: >3.84E+5nMAssay Description:Inhibition of ovine COX1 by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246486(3,3',5-Trihydroxy-2'-methoxybibenzyl (3))
Affinity DataIC50:  6.91E+3nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed