BDBM246496 2,5-Dihydroxy-7-methoxy-9,10-dihydrophenanthrene (14)

SMILES COc1cc(O)c-2c(CCc3cc(O)ccc-23)c1

InChI Key InChIKey=RDKDIPDDUFMMMT-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 246496   

TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Seoul National University

LigandPNGBDBM246496(2,5-Dihydroxy-7-methoxy-9,10-dihydrophenanthrene (...)
Affinity DataKi:  4.96E+3nM ΔG°:  -7.52kcal/mole IC50:  2.51E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246496(2,5-Dihydroxy-7-methoxy-9,10-dihydrophenanthrene (...)
Affinity DataIC50: >4.12E+5nMAssay Description:Inhibition of ovine COX1 by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246496(2,5-Dihydroxy-7-methoxy-9,10-dihydrophenanthrene (...)
Affinity DataIC50:  4.54E+4nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed