BDBM24768 5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-2-[(4-fluorophenyl)amino]-3-methyl-3,4-dihydropyrimidin-4-one::pyrimidone, 50
SMILES COc1cc2nccc(Oc3ccc(cc3F)-c3cnc(Nc4ccc(F)cc4)n(C)c3=O)c2cc1OC
InChI Key InChIKey=DUTNABYDBFVZOA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 24768
Affinity DataKi: 14nM ΔG°: -10.6kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
Affinity DataKi: 382nM ΔG°: -8.66kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair