BDBM2478 17-[3-(dimethylamino)propyl]-7-methyl-6,7,14,17-tetraazatetracyclo[12.4.0.0^{2,6}.0^{8,13}]octadeca-2,4,8(13),9,11-pentaene-15,18-dione::Pyrrolobenzothiadiazepine (PBTD) 16c

SMILES CN(C)CCCN1CC(=O)n2c3ccccc3n(C)n3cccc3c2=C1O

InChI Key InChIKey=AJZUJFLCHNXZSN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2478   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2478(17-[3-(dimethylamino)propyl]-7-methyl-6,7,14,17-te...)
Affinity DataIC50:  2.40E+4nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed