BDBM247994 US9434724, 65

SMILES Cc1cc(Cl)c2c(c[nH]c2c1)C(=O)OCC12CCN(CC1)CC2

InChI Key InChIKey=DCZGNMUEAXUIHE-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 247994   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Alpharmagen

US Patent
LigandPNGBDBM247994(US9434724, 65)
Affinity DataKi:  54.6nM ΔG°:  -10.3kcal/mole IC50:  63.6nMpH: 7.4 T: 2°CAssay Description:Protocol 1: The assay was conducted following the literature reference Meyer E. M., et al., Analysis of 3-(4-Hydroxy, 2-Methoxybenzylidene) Anabasein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Alpharmagen

US Patent
LigandPNGBDBM247994(US9434724, 65)
Affinity DataIC50:  2.43E+3nMpH: 7.4Assay Description:hERG study was conducted with an automated patch clamp machine, Qpatch-48HT (Sophion Biosciences, Denmark). Cultured CHO cells stably expressing hERG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent