BDBM249479 US9434727, 77
SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CCc23)C#N)c1C(F)(F)F
InChI Key InChIKey=ZYYHTMQCCRJZEY-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 249479
Affinity DataIC50: 1.62nMpH: 7.5 T: 2°CAssay Description:TR-FRET assay for retinol-induced RBP4-TTR interaction Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR inte...More data for this Ligand-Target Pair
Affinity DataIC50: 2.88nMpH: 7.4 T: 2°CAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair