BDBM249479 US9434727, 77

SMILES Fc1cccc(C2CCN(CC2)C(=O)c2n[nH]c3CN(CCc23)C#N)c1C(F)(F)F

InChI Key InChIKey=ZYYHTMQCCRJZEY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 249479   

TargetRetinol-binding protein 4(Homo sapiens (Human))
Columbia University

US Patent
LigandPNGBDBM249479(US9434727, 77)
Affinity DataIC50:  1.62nMpH: 7.5 T: 2°CAssay Description:TR-FRET assay for retinol-induced RBP4-TTR interaction Binding of a desired RBP4 antagonist displaces retinol and induces hindrance for RBP4-TTR inte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinol-binding protein 4(Homo sapiens (Human))
Columbia University

US Patent
LigandPNGBDBM249479(US9434727, 77)
Affinity DataIC50:  2.88nMpH: 7.4 T: 2°CAssay Description:Untagged human RBP4 purified from urine of tubular proteinuria patients was purchased from Fitzgerald Industries International. It was biotinylated u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent