BDBM251682 US10100018, Example 18::US9464060, 18

SMILES OC(=O)c1ccc(CN(CC2CC2c2ccccc2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1

InChI Key InChIKey=FDOHMOXGKUEJTN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 251682   

TargetLysophosphatidic acid receptor 5(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM251682(US10100018, Example 18 | US9464060, 18)
Affinity DataIC50:  2nMT: 2°CAssay Description:Engagement of the LPA5 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM251682(US10100018, Example 18 | US9464060, 18)
Affinity DataIC50:  2nMT: 2°CAssay Description:Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM251682(US10100018, Example 18 | US9464060, 18)
Affinity DataIC50:  1nMT: 2°CAssay Description:Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM251682(US10100018, Example 18 | US9464060, 18)
Affinity DataIC50:  1nMT: 2°CAssay Description:Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent