BDBM251890 US9475809, 2::US9918969, 2

SMILES CN1Cc2c(C1=O)c(cc(=O)n2CC(=O)Nc1ccc(cc1)-c1nnn[nH]1)-c1cc(Cl)ccc1Cl

InChI Key InChIKey=OKGUBDLIABPBFJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 251890   

TargetCoagulation factor XI(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM251890(US9475809, 2 | US9918969, 2)
Affinity DataIC50:  340nMAssay Description:The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM251890(US9475809, 2 | US9918969, 2)
Affinity DataIC50:  340nMpH: 7.4 T: 2°CAssay Description:The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent