BDBM251892 US9475809, 4::US9918969, 4

SMILES OC(=O)c1ccc(NC(=O)Cn2c3CCC(=O)c3c(cc2=O)-c2cc(Cl)ccc2Cl)cc1

InChI Key InChIKey=FZEIVJNFDJHITK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 251892   

TargetCoagulation factor XI(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM251892(US9475809, 4 | US9918969, 4)
Affinity DataIC50:  420nMAssay Description:The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM251892(US9475809, 4 | US9918969, 4)
Affinity DataIC50:  420nMpH: 7.4 T: 2°CAssay Description:The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent